Use of Dexpanthenol Combined with Hydroxypropylcellulose in Ocular Surface Disorders Therapy.
str. 44 – 52
Autorzy: Ewelina Trojacka1, Justyna Izdebska1,2, Jacek P. Szaflik.1,2
1 Samodzielny Publiczny Kliniczny Szpital Okulistyczny w Warszawie
2 Katedra i Klinika Okulistyki Wydziału Lekarskiego Warszawskiego Uniwersytetu Medycznego
Kierownik: prof. dr hab. n. med. Jacek P. Szaflik
Ocular surface disorders caused by tear film abnormalities are common clinical problems. Using artificial tears is basic therapy, that helps the ocular surface to regain balance. Osmoprotectants are important ingredients of commonly available lubricants, because of their anti-inflammatory properties and ability to restore tear film. An example of osmoprotectant is hydroxypropylcellulose. Nevertheless, also epithelial regeneration is helpful in ocular surface disease therapy. Dexpanthenol is known as a compound, that supports regeneration of epithelial cells. Nowadays postoperative ocular surface disorders, secondary to the development of ophthalmic surgery, play an important role in many cases of eye surface diseases. Due to complicated etiopathogenesis, postoperative ocular surface disorders, require complex regenerating therapy. A combination of osmoprotectant and a pro-regenerating compound is a beneficial therapeutic option for patients with moderate to severe dry eye disease, also those who suffer from iatrogenic-posttraumatic or postoperative eye surface disorders.