Anterior Segment of the Eye in Patients with Type 2 Diabetes Mellitus
str. 14 – 17
Autorzy: Magdalena Mazurek-Wolińska 1 , Danuta Karczewicz 1 , Wojciech Lubiński 1 , Maria Pietrzak-Nowacka 2
1 II Klinika Okulistyki Pomorskiego Uniwersytetu Medycznego w Szczecinie
Kierownik: prof. dr hab. n. med. Wojciech Lubiński
2 Klinika Nefrologii, Transplantologii i Chorób Wewnętrznych Pomorskiego Uniwersytetu Medycznego w Szczecinie
Kierownik: prof. dr hab. n. med. Kazimierz Ciechanowski
Summary: Introduction: International Diabetes Federation estimated that in 2017 about 451 million people in the world have had diabetes. This number increases constantly in all age groups. Diabetes is a chronic metabolic disease that leads to serious complications in the eye. These changes may also affect the anterior segment of the eye.
Aim: Assessment of changes in the anterior segment of the eye in patients with type 2 diabetes compared to the control group of people without diabetes.
Methods: The study group consisted of 21 patients (42 eyes) with type 2 diabetes, including 7 patients (14 eyes) without diabetic changes in the fundus examination, 7 patients (14 eyes) with nonproliferative diabetic retinopathy, 7 patients (14 eyes) with proliferative diabetic retinopathy. All patients from the study group were under care of the SPSK nr 2 Diabetes Clinic in Szczecin.
The control group with the same age as study group consisted of 21 subjects (42 eyes). The anterior segment assessment performed in each patient included biomicroscopy, Schirmer test I, the assessment of lid-parallel conjunctival folds, tear break-up time, central corneal thickness, endothelial cell density, lens thickness evaluation, anterior chamber depth, lens opacity rating using Lens Opacity Classification System III. HbA1c levels were determined by the Central Laboratory of No. 2 University Hospital in Szczecin.
Results: Patients with type 2 diabetes had more advanced dry eye syndrome, higher degree of lens opacities, decreased corneal endothelial cell density and increased central corneal thickness. No changes in anterior chamber depth and lens thickness were observed in patients with type 2 diabetes.
Conclusions: The results of this study indicate that abnormalities in the structures of the anterior segment of the eye are more common in patients with type 2 diabetes.