Peripheral Retinal Degenerations in Patients with Age-related Macular Degeneration in Ultra-widefield Autofluorescence Fundus Imaging
str. 93 – 95
Autorzy: Joanna Dolar-Szczasny, Anna Święch-Zubilewicz, Jerzy Mackiewicz
Klinika Chirurgii Siatkówki i Ciała Szklistego Uniwersytetu Medycznego w Lublinie
Kierownik: dr hab. n. med. Jerzy Mackiewicz
Summary: Imaging of changes in peripheral retina has become possible after introducing wide field cameras. Fundus autofluorescence is noninvasive examination reflecting retinal pigment epithelium disturbances. Purpose of our study was to present current results concerning peripheral fundus autofluorescence imaging in patients with age-related macular degeneration.
We analyzed already published results with peripheral autofluorescence examinations using ultra-widefield OPTOS instrument. Disturbances in peripheral retina visible in fundus autofluorescence imaging are diagnosed in majority of age-related macular degeneration patients. These hypo- or hiperautofluorescence changes may have different shape and distribution (pattern) and are statistically more prevalent in age-related macular degeneration patients compared to control eyes.
These data may give rise to assumption that degeneration process is not only present in macular area but involves the entire retina with various phenotypes in age-related macular degeneration patients. Identification of these phenotypes may be important for predicting a patient’s response to specific therapeutic options.