Wydanie 1/2004

Zespół Vogta-Koyanagi-Harady

Vogt-Koyanagi-Harada Syndrome

Gabriela Delong, Andrzej Stankiewicz

Klinika Okulistyczna Wojskowego Instytutu Medycznego w Warszawie Kierownik: prof. dr hab. med. Andrzej Stankiewicz


Summary: The Voght?Koyanagi?Harada syndrome, which is probably the result of autoimmune mechanism, is a bilateral, granulomatous uveitis associated with neurological and auditory disorders, alopecia, vitiligo and poliosis. Fluorescein angiography, echography, lumbar puncture are important diagnostic tools. Cataract, glaucoma, optic atrophy, chronic pigmentary changes in the fundus and subretinal neovascular membranes are the most common complications of VKH, which may lead to decrease in visual acuity. Early, systemic, high-dose corticosteroids therapy is desirable, which minimizes complications and improves visual outcome.

Keywords: Vogt-Koyanagi-Harada syndrome, darkly pigmented race, granulomatous uveitis, inflammation, choroidal melanocytes, corticosteroids, cyclosporine, fluorescein angiography, echography, lumbar puncture, cataract, glaucoma, subretinal neovascular membranes.


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