Wydanie specjalne kwiecień 2004

Analogi prostaglandyn - nowe możliwoúci leczenia jaskry i nadciúnienia ocznego

Prostaglandin analogues - new possibilities in glaucoma and ocular hypertension treatment

Dorota Matusiak1, Robert Grabowski2, Janusz Czajkowski1

1Klinika Okulistyki Instytutu Centrum Zdrowia Matki Polki w Łodzi
Kierownik: prof. dr hab. med. Janusz Czajkowski
2Alcon Polska, Warszawa


Summary: Prostaglandin analogues are the newest group of drugs used in glaucoma and ocular hypertension treatment. They have an unique mechanism of action leading to increasing an outflow facility instead of inhibiting aqueous humor production. This is better from physiological point of view. What is more, they give the strongest hypotensive effect and few topical and systemic side effects. They are very useful in effective fight against this group of illnesses like glaucomatous neuropathy.

Keywords: glaucoma, prostaglandin analogues, metalloproteinase, conventional outflow, trabecular meshwork, unconventional outflow, uveoscleral outflow pathway.


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