Wydanie 3/2007

Zastosowanie terapii fotodynamicznej w leczeniu przewlekłej centralnej chorioretinopatii surowiczej - opis przypadku

Chronic Central Serous Chorioretinopathy After Photodynamic Therapy - Case Report

Sława Kwiecień, Maria Kmera-Muszyńska, Jerzy Szaflik

Katedra i Klinika Okulistyki II Wydziału Lekarskiego Akademii Medycznej w Warszawie Samodzielny Publiczny Kliniczny Szpital Okulistyczny w Warszawie Kierownik: prof. dr hab. n. med. Jerzy Szaflik


Summary: Central serous chorioretinopathy (CSC) is characterized by serous retinal detachment localized in the macular region due to the breakdown in the outer blood-retinal barrier (at the retinal pigment epithelium – RPE). Type A personality (competitive drive, sense of urgency, aggressive nature, and hostile temperament) may be a risk factor for its’ development. Most cases of CSC are self-limited. Vision usually returns to normal, although many patients have subtle changes in central or color vision. Patients often develop recurrent leaks in one or both eyes over the years. Chronic and recurrent CSC can be visually disabling in these patients. Macular RPE atrophy with associated atrophic photoreceptor degeneration and choroidal neovascularization (CNV) may accompany chronic and recurrent cases. We present cause of 45 years old male patient with chronic CSC with severe visual loss up to the light perception, in whom we performed photodynamic therapy (PDT). Our analysis confirm, that in difficult and more advanced lesions due to chronic CSC PDT performing can be effective. Verteporfin therapy regimen in eyes with chronic CSC demands further investigation.

Keywords: breakdown in the outer blood-retinal barrier, choroidal vascular hyperpermeability, macular RPE atrophy, photodynamic therapy (PDT)


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